Prevalence of tuberculosis and risk of pulmonary tuberculosis in close contacts of patients in a penitentiary center in the municipality of Palmira, Colombia
DOI:
https://doi.org/10.18041/2665-427X/ijeph.1.5185Keywords:
prison, prisoners, pulmonary tuberculosis, latent tuberculosis, riskAbstract
Introduction: Latent tuberculosis in penitentiary institutions is more frequent. Factors such as overcrowding, malnutrition and limited access to health services increased the risk of reactivation, transmission and poor prognosis.
Objective: To determine the prevalence of latent tuberculosis infection and describe risk factors associated to inmates of a prison.
Methods: Multi-method Operational Research. Cross-sectional study. Prospective follow-up was carried out through the epidemiological surveillance records of the TB control program to determine the prevalence of Pulmonary tuberculosis in the following two years, and risk factors for developing pulmonary tuberculosis in the population of inmates.
Results: Of 2,837 inmates incarcerated (2015-2016), 10.0% were close contact of patients with pulmonary tuberculosis. Overall prevalence of TST positivity was 90.7%, and 92.5% in the population with BCG scar. When were compared to population of inmates + vs population of inmates - groups, those inmates allocated in yard #1 were more likely to be TST+ (p = 0.008). When comparing the groups latent vs active TB, statistical significance was found with having a BMI less than or equal to 18.5 (p = 0.027), OR 5.385 (CI 1.016-28.53). The indirect follow-up through surveillance records showed nine inmates tuberculosis 2 years after the initial diagnosis.
Conclusion: The prison permit concentrate and magnifies determinants that favor the tuberculosis transmission and development to active tuberculosis, which demands strategies for tuberculosis prevention, humanization of the conditions of the population of inmates, and improvement of the health condition.
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References
WHO. Global Tuberculosis Report Executive Summary. 2018; Available from: http://www.who.int/tb/publications/global_ report/tb18_ExecSum_web_4Oct18.pdf
Nogueira PA, Cabral RM, Neder VM, Mendoza RV, Navarro PD, Ceccato KM, et al. Prevalence of latent Mycobacterium tuberculosis infection in prisoners. J Bras Pneumol 2016; 42(5): 348–55
Delgado AHM, González ML, Valdés GML, Hernández MS, Montenegro CT, Rodríguez BDG. Estratificación de riesgo de tuberculosis pulmonar en consejos populares del municipio Cienfuegos. MediSur. 2015; 13(2): 275–84.
Al-Darraji HAA, Razak HA, Ng KP, Altice FL, Kamarulzaman A. The Diagnostic Performance of a Single GeneXpert MTB/RIF Assay in an Intensified Tuberculosis Case Finding Survey among HIV-Infected Prisoners in Malaysia. PLoS One. 2013;8(9): e73717.
Navarro PD, Almeida IN, Kritski AL, Ceccato MG, Maciel MM, Carvalho WS, et al. Prevalence of latent Mycobacterium tuberculosis infection in prisoners. J Bras Pneumol. 2016;42(5):348–55. Doi: 10.1590/S1806-37562016000000001
Ayala G, Garay J, Aragon M, Decroo T, Zachariah R. Trends in tuberculosis notification and treatment outcomes in prisons: a country-wide assessment in El Salvador from 2009-2014. Rev Panam Salud Publica. 2016; 39(1): 38–43.
Ministerio de Salud. Análisis de la situación epidemiológica de la tuberculosis en el Perú 2015. Lima, Perú: Dirección General de Epidemiologia; 2016. Available from: http://www.dge.gob.pe/ portal/index.php?option=com_content&view=article&id=599&It emid=204.
Alarcón-Robayo JF, Martinez-Casallas L, Samir-Sánchez M, Valderrama-Mendoza JS, Bados-Enriquez DM, Jiménez-Canizales CE. Prevalencia de tuberculosis pulmonar en población privada de la libertad de 10 centros penitenciarios en Colombia, 2013. Acta Médica Peruana. 2016; 33(3): 202–7.
MacIntyre CR, Kendig N, Kummer L, Birago S, Graham NMH. Impact of tuberculosis control measures and crowding on the incidence of tuberculous infection in Maryland prisons. Clin Infect Dis 1997; 24: 1060–1067.
Solé N, Marco A, Escribano M, Orcau A, Quintero S, del Baño L, et al. Prevalencia de infección tuberculosa latente en población inmigrante que ingresa en prisión. Rev Española Sanid Penit. 2012;14(1):12–8.
Sacchi F, Praça RM, Tatara MB, Simonsen V, Ferrazoli L, Croda MG, et al. Prisons as Reservoir for Community Transmission of Tuberculosis, Brazil. Emerg Infect Dis. 2015; 21(3): 452–455. Doi: 10.3201/eid2103.140896.
Díaz HO, Torres SE, Fernandez AJ, Gómez MP. Factores de riesgo asociados a la tuberculosis pulmonar. Municipio de Guacara. Estado Carabobo. Venezuela. Enero 2004-mayo 2007. Rev Medica electrónica. 2011; 33(1): 1-7.
Alavi SM, Bakhtiarinia P, Eghtesad M, Albaji A, Salmanzadeh S. A Comparative Study on the Prevalence and Risk Factors of Tuberculosis Among the Prisoners in Khuzestan, South-West Iran. Jundishapur J Microbiol. 2014; 7(12): 1–7. Doi: 10.5812/jjm.18872
Kalonji GM, De Connick G, Okenge Ngongo L, Kazumba Nsaka D, Kabengele T, Tshimungu Kandolo F, et al. Prevalence of tuberculosis and associated risk factors in the Central Prison of Mbuji-Mayi, Democratic Republic of Congo. Trop Med Health. 2016; 44: 30. Doi: 10.1186/s41182-016-0030-9 7
Workicho A, Kassahun W, Alemseged F. Risk factors for multidrug-resistant tuberculosis among tuberculosis patients: A case-control study. Infect Drug Resist. 2017; 10: 91–96. doi: 10.2147/IDR.S126274.
López PMP. Informe del Evento Tuberculosis, Colombia, 2017. Bogota: INS; 2018. Disponible en: https://www.ins.gov.co/ buscador-eventos/Informesdeevento/Tuberculosis%202017.pdf.
Fair E, Miller CR, Ottmani SE, Fox GJ, Hopewell PC. Tuberculosis contact investigation in low- and middle-income countries: standardized definitions and indicators. Int J Tuberc Lung Dis. 2015;19(3):269-72
CDC. Targeted tuberculin testing and treatment of latent tuberculosis infection. MMWR. 2000; 49 (No. RR-6). http://www.cdc.gov/MMWR/PDF/rr/ rr4906.pdf
Dye C, Scheele S, Dolin P, Pathania V, Raviglione MC. WHO Global Surveillance and Monitoring Project. Global Burden of Tuberculosis: Estimated Incidence, Prevalence, and Mortality by Country. JAMA. 1999; 282(7): 677. DOI: 10.1001/jama.282.7.677
Del Corral H, París SC, Marín ND, Marín DM, López L, Henao HM, et al. Respuesta de IFNγ a Mycobacterium tuberculosis, riesgo de infección y enfermedad en contactos domésticos de pacientes con tuberculosis en Colombia. PloS one. 2009; 4(12): e8257.
García-Guerrero J, Mouriño AM, de la Hoya ZPS, Vera-Remartínez EJ. Estudio multicéntrico de prevalencia de infección tuberculosa latente en los internados en prisiones españolas. Rev Española Sanidad Penitenciaria. 2010; 12(3): 79-85.
Rueda ZV, López L, Vélez LA, Marín D, Giraldo MR, Pulido H, et al. High incidence of tuberculosis, lowsensitivity of current diagnostics cheme and prolonged culture positivity in four Colombian prisons. A cohort study. PLoS One. 2013;8(11):1–9.
Rueda ZV, Arroyave L, Marin D, Lopez L, Keynan Y, Giraldo MR, et al. Alta prevalencia y factores de riesgo asociados con infección tuberculosa latente en dos cárceles colombianas. Rev Internacional Tuberculosis Enfermedad pulmonar. 2014; 18(10): 1166-1171
World Health Organization. Guidelines on the management of latent tuberculosis infection, 2015. WHO/HTM/TB/2015.01. WHO; 2015.
Arroyave L, Keynan Y, López L, Marin D, Arbeláez MP, Rueda ZV. Negative latent tuberculosis at time of incarceration: identifying a very high-risk group for infection. Epidemiol Infect. 2017; 145(12), 2491-2499.
Canetti G, Sutherland I, Svandova E. Endogenous reactivation and exogenous reinfection: their relative importance with regard to the development of non-primary tuberculosis. Bull International Union Against Tuberculosis. 1972; 47: 116.
Nogueira PA, Cabral RM, Neder VM, Mendoza RV, Navarro PD, Ceccato K M, Carvalho W, et al. Prevalence of latent Mycobacterium tuberculosis infection in prisoners. J Bras Pneumol. 2016; 42(5): 348–55.
Ferreira MM, Ferrazoli L, Palaci M, Salles PS, Medeiros LA, Novoa P, et al. Tuberculosis and HIV infection among female
inmates in Sao Paulo, Brazil: a prospective cohort study. J Acquir Immune Defic Syndr Hum Retrovirol 1996; 13: 177–183.
MacIntyre CR, Kendig N, Kummer L, Birago S, Graham NMH, Plant AJ. Unrecognised transmission of tuberculosis in prisons. European journal of epidemiology. 1999; 15(8): 705-709.
Dara M, Chadha SS, Vinkeles MNV, van den Hombergh J, Gurbanova E, Al-Darraji H, et al. Time to act to prevent and control tuberculosis among inmates. Int J Tuberc Lung Dis. 2013; 17: 4–5.
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