Efetividade e segurança do uso de micronutrientes em pó no tratamento de crianças com anemia: revisão sistemática
DOI:
https://doi.org/10.18041/1900-3803/entramado.2.5737Palavras-chave:
Micronutrientes em Pó (MNP), anemia, crianças, revisão sistemática, hemoglobinaResumo
Objetivo: Estimar a eficácia do uso de micronutrientes em pó em comparação com outras intervenções no tratamento de crianças com anemia. Metodologia: Foi realizada uma revisão sistemática nos seguintes bancos de dados: Medline, EMBASE, CENTRAL, LILACS, Psycinfo, Clinicaltrials.gov, Google scholar, cinza aberto e anais de conferências. Sem restrição de idioma, foram incluídos ensaios clínicos controlados até janeiro de 2017. Resultados: foram identificados 14.735 artigos; 3 estudos preencheram os critérios de inclusão: Kounnavong, 2011, Lemaire, 2011 e Hirve, 2007. Kounnavong concluiu que a suplementação de MNP teve efeitos positivos na redução da prevalência de anemia e na melhoria da concentração de hemoglobina; Hirve mostrou um aumento significativo na hemoglobina em 3 e 8 semanas em todos os grupos, sem diferenças significativas entre eles. No estudo de Lemaire, a hemoglobina foi maior em indivíduos randomizados no grupo que recebeu MNP aos 2 meses. Conclusões: Não é possível estimar a eficácia do uso de micronutrientes em pó em comparação com outras intervenções para o tratamento de crianças com anemia, devido à insuficiência e heterogeneidade clínica dos estudos incluídos.
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