Immunotherapy toxicity in cancer: an oncology view for the internist

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Keywords

inmunoterapia
tratamiento del cancer
puntos de control del sistema inmune.
eventos adversos de inmunoterapia.
Efectos adversos
toxicidad
quimioterapia
cáncer
antígeno 4 de Linfocitos-T citotóxicos
anticuerpos anti-PD1
anticuerpos anti-PDL1
hepatotoxicidad
hepatitis
meningitis
tiroiditis Immunotherapy
cancer treatment
Immune Checkpoint Blockade
immune-related adverse events
Adverse events
PD-1 inhibitor
PD-L1 inhibitor
programmed cell death 1 inhibitor
cancer immunotherapy
CTLA-4
anti-CTLA4

How to Cite

Ahmad Kanan, A. T., López Ordoñez , C., Riveros-Bermúdez , S. D. ., & Corredor-Rengifo , D. (2023). Immunotherapy toxicity in cancer: an oncology view for the internist. Interdisciplinary Journal of Epidemiology and Public Health, 5(2), e–9900. https://doi.org/10.18041/2665-427X/ijeph.2.9900 (Original work published December 30, 2022)

Abstract

Immunotherapy is considered one of the most recent advances in cancer treatment. Thanks to the technological advances developed in the last three decades in immunology and oncology, we have seen a promising uprising on the treatment of different oncological pathologies through the use of the patient's immune system, especially with the development of antibodies directed against various checkpoints of the immune system (Immune Checkpoint Blockade). A brief review of the pathophysiological mechanism of the most frequent irEAs reported in the literature will be done, as well as their incidence and prevalence according to the different immunotherapy drugs available for treating different solid and hematologic neoplasms.

https://doi.org/10.18041/2665-427X/ijeph.2.9900
PDF (Español (España))
Texto (Español (España))

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