Prediabetes: a difficult decision in pharmacological treatment
DOI:
https://doi.org/10.18041/2665-427X/ijeph.1.10267Keywords:
Prediabetic state, hyperglycemia, treatment, type 2 diabetes mellitus, primary preventionAbstract
Diabetes Mellitus type 2 (DM2) is the most common type and represents more than 90% of all diabetics worldwide. Therefore, the aim is to intervene early in the health-disease cycle that leads to this pathology. It has been possible to establish prediabetes as a stage prior to the development of diabetes, and consequently, it is important to delay or avoid this progression, which can occur in up to 10% of patients. Primary intervention in the prediabetic stages is of utmost importance. This treatment should be based on an intensive program of lifestyle changes as the basis of management. In addition, drugs have been studied which are individualized according to the treatment objective. Among these are metformin, with evidence in special population groups, GLP1 analogs as well as ISGLT2. But for these latter classes, there is still insufficient evidence.
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