Behçet syndrome: Disease of the silk route

Abstract

Behect`s disease is a variable vessel multysistemic vasculitic inflamatory disorder characterized by recurrent oral, genital, aphtous ulcers, posterior bilateral panuveitis, joint manifestations and occasionally compromiso of the central nervous system and large vessels. The varied clinical mmanifestations and the lack of pathognomonic test make the disease a diagnostic challenge whose prevalence in Colombia is unknown. The diagnosis is bases on diagnostic criterio proposed in absence of a Gold Estandard test. Regarding the etiology, varios theories have been studied incluiding those of inmunological origin especially due to the existence of HLA-B51, followed by those that blame infectious agents,endotelial damage among others. A case is presented, corresponding to a famale patient of 35 years og age with chronic and recurrent symptoms of oral trush, the presence of dermatological lesions and the appearance of genital ulcers is presented. Discarding inmunomediated, infectious and inflammatory causes. Considering a picture of recurrent bipolar aphtosis and faced with dermatológical symptoms, it vas proposes to apply the diagnostic criterio of the International Team for the Revision of the Internacional Criteria for Behcet Disease with a score of 4, which supports the diagnosis of Behcets disease. Management was based on the introduction of therapeutic measures bases on systemic corticosteroids and immunosuppressants, with an adequate clinical reponse.