Relationship between colposcopy and biopsy in diagnosis of CA de cervix
DOI:
https://doi.org/10.18041/2390-0512/biociencias.2.7346Keywords:
Colposcopy, Biopsy, Cervical cancerAbstract
To determine the relationship between Colposcopy and biopsy in the diagnosis of cervical cancer in patients aged 18 to 59 years, from the city of Barranquilla, during January to June 2019. Materials and methods: Descriptive, longitudinal, retrospective study. The study area was the Gynecological Diagnostic Service of the Clínica Semin in Barranquilla and the Pathology area, where 565 colposcopy and 53 biopsies results were taken. The results obtained from the relationship between the two main variables are described using percentages and sensitivity and specificity values. Results: The average age of the participants was 40.3 years (SD +/-: 12.8); Colposcopy results showed that 79.2% of the reports indicated suggestiveness for low-grade LIE and 3.8% suggestive for high-grade LIE. In the biopsies, 69.8% of the reports indicated low-grade, while only one case was identified as high-grade. Relating the two results found a sensitivity of 100%, a specificity of 97.8%, but with a positive predictive value of 50% and a negative predictive value of 100%. Conclusion: Almost all low-grade lesions found by colposcopy are confirmed by biopsy; however, a larger sample is required to confirm the sensitivity and specificity of the procedure.
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(1) Arbyn M, Weiderpass E, Bruni L, de Sanjosé S, Saraiya M, Ferlay J, Bray F. Estimates of incidence and mortality of cervical cancer in 2018: a worldwide analysis. The Lancet Global Health, 2020; 8(2): e191-e203.
(2) Ferlay J, Soerjomataram I I, Dikshit R, Eser S, Mathers C, Rebelo M, et al. Cancer incidence and mortality worldwide: sources, methods and major patterns in GLOBOCAN 2012. Int J Cancer [Internet]. 2015;136(5): E359-386
(3) Ministerio de Salud. Resolución 247 [Internet]. Colombia: Imprenta Nacional de Colombia; 2014. Disponible en: http://www.imprenta.gov.co/diariop/diario2.mostrar_norma?p_tipo=03&p_numero=000247&p_ fecha=03/02/2014&p_consec=1330600
(4) Acuña L, Sánchez P, Uribe D, Pulido D, Valencia O. Situación del cáncer en Colombia 2015 [Internet]. 2015.a ed. Bogotá D.C.: Cuenta de Alto Costo; 2015. 336 p. Disponible en: https://cuentadealtocosto.org/ site/images/Situación del Cancer en Colombia 2015.pdf
(5) Uribe Parra D, Pulido D, Lopes G, Sanchez Martinez P, Merchan LA, Estupinan OV, et al. Cancer Incidence in Patients Diagnosed with Acquired Immunodeficiency Syndrome (AIDS) in Colombia. J AIDS Clin Res. 2017
(6) Piñeros M, Cendales R, Murillo R, Wiesner C, Tovar S. Cobertura de la Citología de Cuello Uterino y Factores Relacionados en Colombia, 2005. Rev Salud Pública. 2007;9(3):327-41.
(7) Torre L, Siegel R, Ward E, Jemal A. Global cancer incidence and mortality rates and trends—An update. Cancer Epidemiology and Prevention Biomarkers, 2016; 25(1): 16–27.
(8) Torre L, Siegel R, Ward E, Jemal A. Global cancer incidence and mortality rates and trends—An update. Cancer Epidemiology and Prevention Biomarkers, 2016; 25(1): 16–27.
(9) Bruni L, Diaz M, Castellsagué M, Ferrer E, Bosch F, de Sanjosé S. Cervical human papillomavirus prevalence in 5 continents: Meta-analysis of 1 million women with normal cytological findings. The Journal of Infectious Diseases, 2010; 202(12): 1789–1799.
(10) Leyden W, Manos M, Geiger A, Weinmann S, Mouchawar J, Bischoff K, Taplin S. Cervical cancer in women with comprehensive health care access: Attributable factors in the screening process. Journal of the National Cancer Institute, 2005; 97(9): 675–683.
(11) De Kok IM, van der Aa MA, van Ballegooijen M, et al. Trends in cervical cancer in the Netherlands until 2007: has the bottom been reached? Int J Cancer 2011; 128: 2174–81.
(12) Ronco G, Dillner J, Elfström KM, et al. Efficacy of HPV-based screening for prevention of invasive cervical cancer: follow-up of four European randomised controlled trials. Lancet 2014; 383: 524–32.
( ) Smith RA, Andrews KS, Brooks D, et al. Cancer screening in the United States, 2019: A review of current American Cancer Society guidelines and current issues in cancer screening. CA Cancer J Clin 2019; 69: 184–210.
(13) Sarduy Nápoles M. Correlación citohistológica en las neoplasias intraepiteliales cervicales y en la identificación del VPH en esas lesiones. Revista Cubana de Obstetricia y Ginecología, 2009; 35(1): 1-10.
(14) Akhter S, Bari A, Hayat Z. Variability study between Pap smear, Colposcopy and Cervical Histopathology findings. J Pak Med Assoc. 2015;65(12):1295-9.
(15) Warren J, Gullett H, King V. Cervical Cancer Screening and Updated Pap Guidelines. Prim Care Clin Office Prac 2009: 131-49
(16) Rivera J, Vázquez VM, Ilizaliturri S. Correlación colpo-cito-histológica de lesiones intraepiteliales en el diagnóstico temprano de cáncer cervicouterino (CaCu) en 2,722 casos. Enfermedades del tracto genital inferior 2007; 1: 45-6.
( 17) Alonso P, Lazcano EC, Hernández M. Cáncer cervicouterino. Diagnóstico, prevención y control. 1a. Ed. Panamericana; 2010, p. 203-20.
(18) Dhakal R, Makaju R, Sharma S, Bhandari S, Shrestha S, Bastakoti R. Correlation of cervical pap smear with biopsy in the lesion of cervix. Kathmandu Univ Med J, 2016; 14(1): 254-7.
(19) Gupta S, Sodhani P. Why is high grade squamous intraepithelial neoplasia under-diagnosed on cytology in a quarter of cases? Analysis of smear characteristics in discrepant cases. Indian journal of cancer, 2004; 41(3): 104.
(20) Sánchez M, Olivares A, Contreras N, Díaz M. Certeza diagnóstica de la colposcopia, citología e histología de las lesiones intraepiteliales del cérvix. Médica Sur, 2018; 20(2): 95-99.
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