Inhibitory effect of an aqueous extract of Hibiscus sabdariffa Linn, on the oxidation of low-density lipoprotein (LDL)
DOI:
https://doi.org/10.18041/2390-0512/biociencias.1.6358Keywords:
Hibiscus sabdariffa, Antioxidant, Phenols, LDLAbstract
Introduction: Worldwide consumption Hibiscus sabdariffa, has been growing thanks to its high content rich in bioactive compounds such as flavonoids and anthocyanins. Through its calyces it has been used to prevent and treat degenerative diseases such as cancer, cardiovascular abnormalities, and hyperlipidemia. Objective: To evaluate the antioxidant effect of an extract of H. sabdariffa, by means of the low-density lipoprotein oxidation (LDL) assay. Methods: Dehydrated chalices obtained from an own culture were used, obtaining an acuso extract under conditions similar to the usual consumption. The total phenol content was determined using the Folin-Ciocalteu method. Characterized the extract, its antioxidant activity was evaluated by the LDL oxidation test, obtained from a blood sample from three patients without hyperlipidemia. Results: A statistically significant inhibition of LDL oxidation of the extract and its respective control was evidenced in each of the samples (p <0.05). Conclusions: these results demonstrate that H. sabdariffa is a real alternative in the control of hyperlipidemia and reduction of oxidation of LDL, responsible for the formation of atheroma plaque at the level of the arteries. However, the consumption of this plant must be done under controlled conditions and guided by specialists in order to obtain the desired results.
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