Relation and value prognostic of microalbuminuria in acute coronary syndrome
Keywords:
Microalbuminuria, Coronary syndrome, Acute myocardial infarctionAbstract
Objective: To determine the relationship and prognosis value of microalbuminuria in acute coronary syndrome. Materials and Methods: Cross ambispective analytical study in 100 patients with ischemic symptoms of minutes of evolution; in patients with acute myocardial infarction, the criteria used were: Electrocardiographic changes of ST segment elevation not less than 0.1 mV in two bipolar leads or 0.2 mV in at least two contiguous precordial leads, or new blocking left branch of His bundle; in patients with unstable angina criteria were: ischemic electrocardiographic changes or injury, CKMB isoenzyme level less than 10% to total CK. The data were processed using the Epi-Info software version 3.5.3. and absolute frequencies, averages and Pearson correlation coefficient were determined. Results: The male, 64% in patients with AMI and 72% in those with unstable angina, showed the highest frequency; the average age for AMI was 62.5 ± 10.1 years olds; the average age for unstable angina was 60.4 ± 11.0 years olds; the microalbuminuria average in the AMI group was 207.4 ± 64.7 mg and 44.9 ± 40.0 mg in the group with angina. Patients with microalbuminuria> 200 mg were 14.4 times higher risk of complications associated with statistically significant prognostic value. Conclusions: The magnitude of microalbuminuria is directly related to the severity of acute coronary syndrome; higher concentrations are observed in acute myocardial infarction; microalbuminuria> 200 mg is is prognosis of complications.
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2. Cassiani C, Cabrera A. Síndromes coronarios agudos: epidemiología y diagnóstico. Salud Uninorte. 2009; 25 (1): 118-34.
3. Rosamond W, Flegal K, Furie K, Go A, Greenlund K, Haase N, et al. Heart disease and stroke statistics--2008 update: a report from the American Heart Association Statistics Committee and Stroke Statistics Sub committee. Circulation. 2008 ;117(4):25-146
4. Brieger DB. Acute coronary syndromes without chest pain, an underdiagnosed and undertreated highrisk group. Circulation. 2010; 11:96-113.
5. Boland LL, Folsom AR, Sorlie PD, Taylor HA, Rosamond WD, Chambless LE et al. Occurrence of unrecognized myocardial infarction in subjects aged 45 to 65 years (the ARIC study). Am J Cardiol. 2002;90:927-31.
6. Mandelzweig L, Battler A, Boyko V, Bueno H, Danchin N, Filippatos G, et al. The second Euro Heart Survey on acute coronary syndromes: characteristics, treatment, and outcome of patients with ACS in Europe and the Mediterranean Basin in 2004. European Heart Journal. 2006;27:2285- 93.
7. Kannel WB, Hjortland MC, McNamara PM, Gordon T. Menopause and risk of cardiovascular disease: the Framingham study. Ann Intern Med. 1976;85:447- 52.
8. Furman MI, Dauerman HL, Goldberg RJ, Yarzebski J, Lessar D, Gore JM. Twenty-two yaer (1975 to 1997) trends in the incidence, in hospital and long-term case fatality rates from initial Q-wave and no Q-wave myocardial infarction: a multihospital, community-wide perspective. J Am Coll Cardiol. 2001;37:1571-80.
9. Rosamond WD, Chambless LE, Folsom AR, Cooper LS, Conwill DE, Clegg L, et al.Trends in the incidence of myocardial infarction and in mortality due to coronary heart disease. N Engl J Med. 1998;339:861-7.
10. Beltrán JR, Beltrán R, Caicedo VM, García M, García E, Gómez EA, et al. Guías colombianas de cardiología. Síndrome coronario agudo sin elevación del ST. Rev Col Cardiol. 2008;15 Supl 3:143-232.
11. Agamez L, Del Río V, Cano R. Relación de la microalbuminuria con la gravedad del síndrome coronario agudo, E.S.E Alta Complejidad. Rev Biociencias. 2011; 6: 19- 25.
12. Halabe A. Microalbuminuria: Utilidad clínica. An Med Asoc Med Hosp ABC. 1999; 44 (2): 82-5.
13. Hillege HL, Fidler V, Diercks GFH, Van Gilst W, De Zeeuw D, Van Veldhuisen DJ, et al. Urinary albumin excretion predicts cardiovascular and noncardiovascular mortality in general population. Circulation. 2002;106:1777-82.
14. Hackman DG, Anand SS. Emerging risk factors for atherosclerotic vascular disease: a critical review of the evidence. JAMA 2003;290:932-8.