Hipopotasemic tirotoxic periodic paralysis

Report of a case and revision of literature

Authors

  • Alejandro Ochoa Morón Universidad Libre
  • Luis Peréz Rodríguez Universidad Libre

Keywords:

Hipopotasemic tirotoxic periodic paralysis, Tirotoxicosis, Hyperthyroidism, Hypokalemia

Abstract

The hipopotasemic tiroxic periodic paralysis is an entity of low frequency, with incidence of 2 % in the western countries; in our means the incidence is smaller, and predominates between masculine young adults with hyperthyroidism antecedent; clinically one appears like episodes of acute muscular weakness; that they can put in risk the life of the patient; raising a diagnostic challenge occasions about which it does not exist previous antecedent of disease, taking the great majority of the times to think about diagnoses differential slike syndrome of Guillain- Barre-Landry, transverse myelitis, hysteria and acute medullary compression. The following is a patient with picture of acute muscular weakness exposes itself, that raised initially a probable picture of Guillain-Barre-Landry and in which later determined the presence of hyperthyroidism, like causal of hypokalemia and acute muscular weakness, diagnosing finally hipopotasemic tirotoxic periodic paralysis; in addition, a review of the literature is presented.

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References

Asimos, A. Uptodate [página de Internet]. Einpa: Evaluation of the adult with acute weakness in the emergency department 2013. [Actualizado Ene 2013. Citado 26 Marz 2013] (aprox 3 páginas). Disponible en: http://www.uptodate.com /contents/eva- luation-of-the-adult-with-acute-weakness- in-the-emergency-department. abril, 2013. Última actualización, julio 08, 2013.

Orellana C, Durón R, Medina M. Reporte de caso de parálisis hipocalémica periódica y propuesta de abordaje diagnóstico de la pa- rálisis flácida aguda. Rev Med Hond. 2002; 70:182-8.

Frantchez V, Valiño J, Carracelas A, Dufre- chou C. Parálisis periódica hipopotasémica tirotóxica. Caso clínico. Rev Med Chile. 2010; 138:1427-30.

Lin SH, Lin YF, Halpering ML. Hypokalemia and paralysis. QJM 2001; 94:133-9.

Adams RD, Víctor M, Ropper AH. Principles of Neurology, 8th Ed. New York: McGraw- Hill; 2007.

Kung A. Clinical Review: Thyrotoxic periodic paralysis: A diagnostic challenge. J Clin Endo- crinol Metab. July 2006; 91(7):2490-5.

Falhammar H, Thoren M, Calissendorff J. Thyrotoxic periodic paralysis: clinical and molecular aspects. Endocrine. 2013; 43:274- 84.

Ryan DP, Dias da Silva MR, Soong TW, Fontai- ne B, Donaldson MR, Kung A. et al. Mutations in Potassium Channel Kir2.6 Cause Suscepti- bility to Thyrotoxic Hypokalemic Periodic Pa- ralysis. Cell. Jan 8, 2010; 140(1):88-98.

Castillo-Ramírez A, Velázquez-Figueroa JM, Rosales-Salyano VH, Ochoa-Hein E. Parálisis hipocalémica tirotóxica. Informe de un caso y revisión de la bibliografía. Rev Med Hosp Gen Méx. 2011; 74(2):87-91.

Lin, Shih-Hua. Thyrotoxic periodic paralysis. MayoClin Proc. January. 2005; 80(1):99-105.

Wendorf M, Goldfine ID. Archaeology of NIDDM. Excavation of the “thrifty” genoty- pe. Diabetes. 1991; 40:161-5.

Arzel-Hézode M, McGoey S, Sternberg D, Vicart S, Eymard B, Fontaine B. Glucocorti- coids may trigger attacks in several types of periodic paralysis. Neuromuscular Disorders. 2009;19:217-9.

Manoukian MA, Foote JA, Crapo LM. Clinical and metabolic features of thyrotoxic periodic paralysis in 24 episodes. Arch. Intern. Med. 1999; 159(6):601-6.

Hiraga A, Kamitsukasa I, Kojima K, Kuwaba- ra S. Clinical features and recovery patterns of acquired non-thyrotoxic hypokalemic pa- ralysis. Journal of the Neurological Sciences. 2012;313:42-5.

Patel H, Wilches L, Guerrero J. Thyrotoxic periodic paralysis: diversity in America. The Journal of Emergency Medicine. 2013; 1-3.

Lopez S, Henderson S. Electrocardiogram changes in Thyrotoxic Periodic Paralysis. West J Emerg Med. 2012; 13(6):512-3.

Lin, Shih-Hua, Huang, Chou-Long. Mecha- nism of Thyrotoxic Periodic Paralysis. J Am Soc Nephrol; 2012:23.

Maciel RMB, Lindsey SC, Dias da Silva MR. Novel Etiopathophysiologica aspects of thyrotoxic periodic paralysis. Natural Re- views Endocrinology. 2011; 7:657-67, publis- hed online 10 may 2011; doi:10.1038/nren- do.2011.58.

Cope T, Samaraweera AP, Burn DJ. Thyrotoxic periodic paralysis: correct hypokalemia with caution. The Journal of Emergency Medicine. 2013; 45(3): 338-40.

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Published

2013-12-01

Issue

Section

CASE REPORTS

How to Cite

Hipopotasemic tirotoxic periodic paralysis: Report of a case and revision of literature. (2013). Biociencias, 8(2), 61-69. https://revistas.unilibre.edu.co/index.php/biociencias/article/view/2814