CONTROVERSIAS EN RELACIÓN AL DIAGNÓSTICO Y TRATAMIENTO DEL CÁNCER ENDOMETRIAL. UNA ACTUALIZACIÓN.
DOI:
https://doi.org/10.18041/2390-0512/bioc..2.2540Palabras clave:
Cáncerendometrial, Factor de riesgo, ObesidadResumen
Antecedentes: El cáncer endometrial (CE) según las estadísticas es el tumor ginecológico más frecuente en países desarrollados, donde su incidencia ha ido en aumento. Históricamente, el CE se ha clasificado en dos tipos principales clínico-patológicos y moleculares: el tipo I (endometrioide), representando el 80-90% de los casos, el tipo II (subtipos no endometrioides tales como: el de células serosas, claras y carcinomas indiferenciados). Como dato importante, la mayoría de las pacientes son diagnosticadas cuando la enfermedad se encuentra en etapas tempranas, es decir cuando la lesión todavía está confinada al útero. El tratamiento convencional radica en una histerectomía primaria más salpingooforectomía bilateral, ya sea por medio de una laparotomía abdominal o utilizando métodos mínimamente invasivos como la laparoscopia o la laparoscopia asistida por robot.
Objetivo: Actualizar los conocimientos sobre el Diagnóstico y tratamiento del cáncer endometrial, en relación a las diferentes controversias.
Metodología: Se revisó la literatura disponible en inglés en los últimos 5 años hasta el 2016. Utilizando los términos clave: endometrial, cancer, diagnosis y treatment, se accedió a la información mediante una estrategia de búsqueda en la base de datos de MEDLINE, EMBASE, PubMed, ClinicalKey, Ovid y la librería de Cochrane.
Resultados: Existe en la literatura numerosas evidencias científicas que fundamentan desde la perspectiva del cáncer endometrial, la participación de múltiples factores sobre los cuales se define el diagnóstico y tratamiento de las pacientes.
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