Resistencia bacteriana mediada por el gen blaKPC en Klebsiella pneumoniae
DOI:
https://doi.org/10.18041/2323-0320/microciencia..2023.12599Palabras clave:
Klebsiella pneumoniae, Resistencia, Lactámicos, antibióticosResumen
Klebsiella pneumoniae es una bacteria oportunista que produce infecciones hospitalarias causando altas tasas de morbilidad y mortalidad a nivel mundial, su tratamiento se ha visto limitado debido a la resistencia frente a diversos antibióticos incluyendo los de amplio espectro que son los antibióticos ß-lactámicos. Con base en lo anterior el objetivo del presente trabajo es recopilar información sobre los elementos implicados en la resistencia bacteriana en Klebsiella pneumoniae y para ello se empleo la base de datos NCBI donde se encontraron artículos relevantes sobre los antibióticos ß-lactámicos, modo de acción, enzimas encargadas de hidrolizar estos antibióticos además de los genes involucrados en su expresión y los mecanismos involucrados en la movilización de genes y por tanto su relación en la diseminación entre bacterias.
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