The pulmonary-renal syndrome as an initial presentation of multiple myeloma case

Authors

  • Arturo Guzmán Freja Universidad Libre

Keywords:

Multiple myeloma, Acute renal failure, Pulmonary hemorrhage, Pulmo-Renal Syndrome

Abstract

The combined clinical presentation of acute renal failure with pulmonary hemorrhage is known as pulmonary-renal syndrome. A case of a woman of 78 years olds who presented acute renal failure and pulmonary hemorrhage from the onset of symptoms is described. Renal biopsy and bone marrow aspiration showed nephropathy and an abnormal increase in plasma cells, respectively. The patient was diagnosed with Multiple Myeloma and successfully treated with corticosteroids and plasma transfusions. The presentation of this case indicates the need to consider multiple myeloma as a cause of pulmonary- renal syndrome.

Downloads

Download data is not yet available.

References

1. García M, Vela J, Mieloma Múltiple . Epidemilogía, diagnóstico y tratamiento . Hematología, la sangre y sus enfermedades. tercera edición. México: Mc Graw Hill; 2012.

2. Alexanian R, Barlogie B, Dixon D. Renal failure in multiple myeloma. Pathogenesis and prognostic implications. Arch Intern Med. 1990; 150: 1693-95.

3. Kyle RA, Gertz MA, Witzig TE, et al. Review of 1027 patients with newly diagnosed multiple myeloma. Clin Proc. 2003; 78: 21- 33.

4. Bolaman Z, Yavasoglu I, Unubol M, Kadikoylu G. Hemoptysis as a presenting sign of multiple myeloma. Respir Med. 2008; 102: 1672- 73.

5. Russi E, Odermatt B, Joller-Jemelka HI, Spycher MA. Alveolar haemorrhage as a presenting feature of myeloma. Eur Respir J. 1993; 6: 267-70.

6. Kintzer JS, Rosenow EC, Kyle RA. Thoracic and pulmonary abnormalities in multiple myeloma. A review of 958 cases. Arch Intern Med. 1978; 138: 727-30.

7. Eby CS. Bleeding and thrombosis risks in plasma cell dyscrasias. Hematology Am Soc Hematol Educ Program; 2007.

8. El-Achkar TM, Sharfuddin AA, Dominguez J. Approach to acute renal failure with multiple myeloma: role of plasmapheresis. Ther Apher Dial. 2005; 9: 417-22.

9. Johnson WJ, Kyle RA, Pineda AA, O’Brien PC, Holley KE. Treatment of renal failure associated with multiple myeloma. Plasmapheresis, hemodialysis, and chemotherapy. Arch Intern Med. 1990; 150: 863-69.

10. Zucchelli P, Pasquali S, Cagnoli L, Ferrari G. Controlled plasma exchange trial in acute renal failure due to multiple myeloma. Kidney Int.1988; 33: 1175-80.

11. Clark WF, Stewart AK, Rock GA, Sternbach M, Sutton DM, Barrett BJ, et al. Plasma exchange when myeloma presents as acute renal failure: a randomized, controlled trial. Ann Intern Med. 2005; 143: 777-84.

12. Borrego J, Pérez MP, Biechy M, García E, Sánchez M, García MJ, et al. Treatment by long haemodialysis sessions with high cut-off filters in myeloma cast nephropathy: our experience. Nefrología. 2013; 33(4):515-23.

Downloads

Published

2014-12-01

Issue

Section

Articles

How to Cite

The pulmonary-renal syndrome as an initial presentation of multiple myeloma case. (2014). Biociencias, 9(2), 57-63. https://revistas.unilibre.edu.co/index.php/biociencias/article/view/2858