Pyoderma gangrenosum associated with ulcerative colitis
Report of a case
Keywords:
Pyoderma Gangrenosum, Dermatoses, ErythemaAbstract
Gangrenous pyoderma (PG) is an often destructive rare inflammatory skin disease of unknown etiology and pathogenesis, belonging to the spectrum of neutrophilic dermatosis, characterized by papules, pustules, nodules or painful suffering erosion and progressively ulcerate, which is a diagnostic challenge when not counting today with clinical, paraclinical or pathognomonic histopathological this entity. We present a case report of a woman of 60, who attends the service of dermatology with large painful ulcerative lesion in the abdominal wall, pubic region, hip and right thigh along with gastrointestinal symptoms, which ultimately leads to the diagnosis of PG associated with ulcerative colitis.
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References
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2. Brunsting LA, Goeckerman WH, O’Leary PA. Pyoderma Gangrenosum, Clinical and experimental observations in five cases occurring in adults. Arch Dermatol. 1982;743:768-818.
3. Ferri FF. Pyoderma Gangrenosum. Ferri’s Clinical Advisor, 1st ed. Elsevier; 2014.
4. Demidowich AP, Freeman AF, Kuhns DB, Aksentijevich I, Gallin JI, Turner ML, Kastner DL, Holland SM. Brief report: genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne). Arthritis Rheum. 2012; 2022:2027-64.
5. Braun-Falco M, Kovnerystyy O, Lohse P, and Ruzicka T. Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH) a new autoinflammatorysyndrome distinct from PAPA syndrome. J Am Acad Dermatol. 2012; 409:415-66.
6. Brinster NK, Vincent LA, Diwan H, and McKee P H. Pyoderma Gangrenosum.Dermatopathology: High-Yield Pathology, 1st ed. Elsevier; 2011.
7. Hadi A, and Lebwohl M. Clinical features of pyoderma gangrenosum andcurrent diagnostic trends. J Am Acad Dermatol. 2011;64:950-4.
8. Wall LB and Stern PJ. Pyoderma gangrenosum. American Society for Surgery of the Hand. 2012;1083:1085-37.
9. Bhat RM. Pyoderma gangrenosum: An update. Indian Dermatology Journal. 2012; 7:13-3.
10. Calonje E, Brenn T, and Lazar A. Neutrophilic and eosinophilic dermatoses. McKee’s Pathology of the Skin ,4th Ed.; Elsevier; 2012.
11. Berth-Jones J. Pyoderma gangrenosum. Treatment of Skin Disease: Comprehensive Therapeutic Strategies, 4th Ed. Elsevier; 2014
12. Callen JP, Jackson JM. Pyoderma Gangrenosum: An Update. Rheum Dis Clin N Am. 2007;787:802-33.
13 Amor KT, Ryan C, and Menter A. The use of cyclosporine in dermatology. Journal of the American Academy of Dermatology. 2010; 925:946-63.
14. Andrisani G, Guidi L, Papa A, Potenza AE, Cervelli D, Armuzzi A. A case of pyoderma gangrenosum with ulcerative colitis treated with combined approach:Infliximab and surgery. Journal of Crohn’s and Colitis. 2013; 421:426-7.
2. Brunsting LA, Goeckerman WH, O’Leary PA. Pyoderma Gangrenosum, Clinical and experimental observations in five cases occurring in adults. Arch Dermatol. 1982;743:768-818.
3. Ferri FF. Pyoderma Gangrenosum. Ferri’s Clinical Advisor, 1st ed. Elsevier; 2014.
4. Demidowich AP, Freeman AF, Kuhns DB, Aksentijevich I, Gallin JI, Turner ML, Kastner DL, Holland SM. Brief report: genotype, phenotype, and clinical course in five patients with PAPA syndrome (pyogenic sterile arthritis, pyoderma gangrenosum, and acne). Arthritis Rheum. 2012; 2022:2027-64.
5. Braun-Falco M, Kovnerystyy O, Lohse P, and Ruzicka T. Pyoderma gangrenosum, acne, and suppurative hidradenitis (PASH) a new autoinflammatorysyndrome distinct from PAPA syndrome. J Am Acad Dermatol. 2012; 409:415-66.
6. Brinster NK, Vincent LA, Diwan H, and McKee P H. Pyoderma Gangrenosum.Dermatopathology: High-Yield Pathology, 1st ed. Elsevier; 2011.
7. Hadi A, and Lebwohl M. Clinical features of pyoderma gangrenosum andcurrent diagnostic trends. J Am Acad Dermatol. 2011;64:950-4.
8. Wall LB and Stern PJ. Pyoderma gangrenosum. American Society for Surgery of the Hand. 2012;1083:1085-37.
9. Bhat RM. Pyoderma gangrenosum: An update. Indian Dermatology Journal. 2012; 7:13-3.
10. Calonje E, Brenn T, and Lazar A. Neutrophilic and eosinophilic dermatoses. McKee’s Pathology of the Skin ,4th Ed.; Elsevier; 2012.
11. Berth-Jones J. Pyoderma gangrenosum. Treatment of Skin Disease: Comprehensive Therapeutic Strategies, 4th Ed. Elsevier; 2014
12. Callen JP, Jackson JM. Pyoderma Gangrenosum: An Update. Rheum Dis Clin N Am. 2007;787:802-33.
13 Amor KT, Ryan C, and Menter A. The use of cyclosporine in dermatology. Journal of the American Academy of Dermatology. 2010; 925:946-63.
14. Andrisani G, Guidi L, Papa A, Potenza AE, Cervelli D, Armuzzi A. A case of pyoderma gangrenosum with ulcerative colitis treated with combined approach:Infliximab and surgery. Journal of Crohn’s and Colitis. 2013; 421:426-7.
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Published
2014-12-01
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