Toxicological Analysis and Carfentanil Associated Mortality
DOI:
https://doi.org/10.18041/2390-0512/biociencias.1.10636Keywords:
Carfentanil, fentanyl, opioid, chromatographyAbstract
Introduction: the detection of Carfentanil, a dangerous opioid, is critical due to its appearance in other drugs and its high potency. Its consumption carries a series of negative effects such as respiratory depression, hypotension, bradycardia and decreased intestinal motility.
Objectives: the purpose of this systematic review is to examine or evaluate or summarize the main toxicological detection methods related to deaths caused by carfentanil, focusing on the study of the adverse chemical effects it produces in humans.
Methodology: this research collected relevant information in the field of forensic toxicology. Which focused on carfentanil detection methods and how it affects people. PRISMA review guidelines were followed and the PICO strategy was used to define the focus of the study.
Results: different detection methods have been found such as blood, urine, saliva, liver, pericardial fluid and vitreous humor tests. These methods involve the extraction of biological samples and their subsequent analysis using advanced techniques such as chromatography and mass spectrometry. Even advanced techniques, such as portable mass spectrometry, have been developed to rapidly identify the presence of carfentanil in drug samples. However, the availability of these methods in healthcare settings remains limited.
Conclusions: it is crucial to understand the deterioration and damage caused to the body and address the crisis regarding the marketing of this highly dangerous substance. This highlights the urgent need to address this issue and protect society from the risks associated with carfentanil.
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